SECURITIES AND EXCHANGE COMMISSION

Washington D.C. 20549

SCHEDULE 13G

Amendment No. 3

Under the Securities Exchange Act of 1934

GENVEC, INC.

(Name of Issuer)

Common Stock, $0.001 Par Value

(Title of class of Securities)

37246C109

(CUSIP Number)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed.

[ ] Rule 13d-1(b)

[ ] Rule 13d-1(c)

[X] Rule 13d-1(d)

The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior coverage page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of this section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 990,804 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

990,804 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

990,804

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

1.93%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

L. M. Wagner as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 500,000 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

500,000 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

500,000

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.98%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of Juliet Lea Hillman Simonds I.D. #25-6193084

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 125,000

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 125,000

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

125,000

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.24%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of Audrey Hillman Fisher I.D. #25-6193085

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 125,000

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 125,000

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

125,000

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.24%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of Henry Lea Hillman, Jr. I.D.. #25-6193086

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 125,000

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 125,000

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

125,000

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.24%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of William Talbott Hillman I.D. #25-6193087

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 125,000

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 125,000

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

125,000

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.24%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Henry L. Hillman as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 490,804 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

490,804 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

490,804

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.96%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Elsie Hilliard Hillman as Trustee

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

U.S.

Number of 5. Sole Voting Power

Beneficially

Owned by 6. Shared Voting Power

Each 490,804 (See Item (4)(a))

Reporting

Person 7. Sole Dispositive Power

With

8. Shared Dispositive Power

490,804 (See Item (4)(a))

9. Aggregate Amount Beneficially Owned by Each Reporting Person

490,804

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.96%

12. Type of Reporting Person

CUSIP NO. 37246C109

1. Name of Reporting Persons IRS Identification No. of above Persons

(entities only)

Henry L. Hillman, Elsie Hilliard Hillman and C. G Grefenstette

Trustees of the Henry L. Hillman Trust U/A Dated November 18, 1985

I.D. # 18-2145466

2. Check the Appropriate Box if Member of a Group (a) [X]

(b) [ ]

3. SEC Use Only

4. Citizenship or Place of Organization

Pennsylvania

Number of 5. Sole Voting Power

Shares 490,804

Beneficially

Owned by 6. Shared Voting Power

Each

Reporting

Person 7. Sole Dispositive Power

With 490,804

8. Shared Dispositive Power

9. Aggregate Amount Beneficially Owned by Each Reporting Person

490,804

10. Check Box if the Aggregate Amount in Row (ii) Excludes Certain Shares

11. Percent of Class Represented by Amount in Row (11)

.96%

12. Type of Reporting Person

Item 1(a) Name of Issuer

Genvec, Inc.

Item 1(b) Address of Issuer's Principal Executive Office:

65 West Watkins Mill Road

Gaithersburg, Maryland 20878

Item 2(a) Name of Person Filing:

(i) Henry L. Hillman, Elsie Hilliard Hillman and C. G. Grefenstette

Trustees of the Henry L. Hillman Trust U/A dated November 18,

1985 (the "HLH Trust").

(ii) C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of Juliet Lea Hillman Simonds (the "1976 JLHS Trust).

(iii) C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of Audrey Hillman Fisher (the "1976 AHF Trust).

(iv) C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of Henry Lea Hillman, Jr. (the "1976 HLH, Jr. Trust).

(v) C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated 12/30/76

for the Children of William Talbott Hillman (the "1976 WTH Trust).

(vi) Elsie Hilliard Hillman

(vii) Henry L. Hillman

(viii) L. M. Wagner

(ix) C. G. Grefenstette

Item 2(b) Address of the principal Business Office:

The 1976 JLHS Trust, the 1976 AHF Trust, the 1976 HLHJR Trust

the 1976 WTH Trust and the HLH Trust

1900 Grant Building

Pittsburgh, Pa 15219

Elsie Hilliard Hillman, Henry L. Hillman, L. M. Wagner and

C. G. Grefenstette

2000 Grant Building

Pittsburgh, Pennsylvania 15219

Item 2(c) Citizenship:

The 1976 JLHS Trust, the 1976 AHF Trust, the 1976 HLHJR Trust

the 1976 WTH Trust and the HLH Trust are Pennsylvania trusts.

Elsie Hilliard Hillman, Henry L. Hillman, L. M. Wagner and

C. G. Grefenstette are U.S. citizens.

Item 2(d) Title of Class of Securities:

Common Stock, $.001 Par Value

Item 2(e) CUSIP Number

37246C109

Item 3 Not Applicable

Item 4 Ownership:

490,804 shares of Common Stock are owned of record and beneficially

by Henry L. Hillman, Elsie Hilliard Hillman and C. G. Grefenstette,

Trustees of the Henry L. Hillman Trust U/A dated November 18, 1985

a Pennsylvania revocable trust. C. G. Grefenstette shares power to

vote or to direct the vote and shares power to dispose or to direct the

disposition of the shares of stock owned by the 1976 Trusts and the

HLH Trust. Henry L. Hillman shares power to vote or to direct the vote

and shares power to dispose or direct the disposition of the shares of

stock owned by the HLH Trust. Elsie Hilliard Hillman shares power

to vote or to direct the vote and shares power to dispose or to direct the

disposition of the shares of stock owned by the HLH Trust.

125,000 shares of Common stock are owned of record beneficially by

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated

December 30, 1976 for the Children of Juliet Lea Hillman Simonds

(together with the three trusts of even date named below, the "1976

Trusts"), a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts

and the HLH Trust.

125,000 shares of Common stock are owned of record beneficially by

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated

December 30, 1976 for the Children of Audrey Hillman Fisher

(together with the three trusts of even date named, the "1976

Trusts"), a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts

and the HLH Trust.

125,000 shares of Common stock are owned of record beneficially by

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated

December 30, 1976 for the Children of Henry Lea Hillman, Jr.

(together with the three trusts of even date named, the "1976

Trusts"), a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts

and the HLH Trust.

125,000 shares of Common stock are owned of record beneficially by

C. G. Grefenstette and L. M. Wagner, Trustees U/A/T dated

December 30, 1976 for the Children of William Talbott Hillman

(together with the three trusts of even date named below, the "1976

Trusts"), a Pennsylvania irrevocable trust. C. G. Grefenstette shares

power to vote or to direct the vote and shares power to dispose or to

direct the disposition of the shares of stock owned by the 1976 Trusts

and the HLH Trust.

(b) Percent of Class

1.93%

(i) sole power to vote or direct the vote

(ii) shared power to vote or to direct the vote

990,804 (See Item (4)(a))

(iii) sole power to dispose or to direct the disposition of

(iv) shared power to dispose or to direct the disposition of

990,804 (See Item (4)(a))

Item 5 Ownership of Five Percent or Less of a Class:

Not Applicable

SIGNATURES

After reasonable inquiry and to the best of my knowledge and belief, I certify

That the information set forth in this statement is true, complete and correct.

HENRY L. HILLMAN, ELSIE HILLIARD HILLMAN

AND C. G. GREFENSTETTE, TRUSTEES OF THE

HENRY L. HILLMAN TRUST U/A DATED

NOVEMBER 18, 1985

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

C. G. GREFENSTETTE AND L. M. WAGNER, TRUSTEES

U/A/T DATED DECEMBER 30, 1976 FOR THE CHILDREN

OF JULIET LEA HILLMAN SIMONDS

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ L. M. Wagner

L. M. Wagner, Trustee

C. G. GREFENSTETTE AND L. M. WAGNER, TRUSTEES

U/A/T DATED DECEMBER 30, 1976 FOR THE CHILDREN

OF AUDREY HILLMAN FISHER

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ L. M. Wagner

L. M. Wagner, Trustee

C. G. GREFENSTETTE AND L. M. WAGNER, TRUSTEES

U/A/T DATED DECEMBER 30, 1976 FOR THE CHILDREN

OF HENRY LEA HILLMAN, JR.

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ L. M. Wagner

L. M. Wagner, Trustee

C. G. GREFENSTETTE AND L. M. WAGNER, TRUSTEES

U/A/T DATED DECEMBER 30, 1976 FOR THE CHILDREN

OF WILLIAM TALBOTT HILLMAN

/s/ C. G. Grefenstette

C. G. Grefenstette, Trustee

/s/ L. M. Wagner

L. M. Wagner, Trustee

C. G. Grefenstette

L. M. Wagner